Inheritance, variation and evolution
Lesson overview
This lesson introduces the core biology idea, the useful equipment and the calculation or data skills used on this page.
What you will learn
Core knowledge
Inheritance, variation and evolution infographic

DNA practice set
Use the worked examples and practice questions on this page as a complete study task: learn the definitions of DNA and gene, summarise the infographic in your own words, then answer the questions using the data, equations and observations given here. Check every answer for base sequence, scale and probability language.
Clear explanation
First secure the anchor idea: DNA, genes and chromosomes. In ordinary language, this means using DNA, gene and chromosome to explain what is happening, not just spotting those words in the question.
Next look for the evidence. In this lesson it is likely to come from cell-nucleus diagrams, chromosome diagrams, base sequence information, genome contexts and protein-coding prompts.
Then build the answer in order: Understand DNA, genes and chromosomes then use genetic information evidence from cells and proteins then process data with base sequence, scale and probability language. This stops the answer becoming a list of disconnected facts.
If the question includes data, use base sequence, scale and probability language. Keep the unit or comparison visible, then link the result back to DNA or gene.
Exam-ready model sentence: A gene is a section of DNA on a chromosome, and the genome is the full set of genetic information.
Worked examples
DNA: from idea to explanation
Question: Explain DNA, genes and chromosomes using the model.
Start with the idea: Understand DNA, genes and chromosomes.
Add the mechanism: use genetic information evidence from cells and proteins.
Finish with the consequence: process data with base sequence, scale and probability language.
Reveal worked answer
Answer: A good answer uses DNA (the genetic material that carries instructions for making proteins), gene (a section of DNA that codes for a protein or characteristic) and chromosome (a long DNA molecule packaged with proteins in a cell nucleus) in one connected explanation. For example: A gene is a section of DNA on a chromosome, and the genome is the full set of genetic information.
DNA: from evidence to marks
Question: A student has evidence from cell-nucleus diagrams, chromosome diagrams, base sequence information, genome contexts and protein-coding prompts. What should their answer include?
Step 1: name the useful evidence rather than writing a general fact about the topic.
Step 2: process any data with base sequence, scale and probability language.
Step 3: explain what the evidence shows about DNA and gene.
Reveal worked answer
Answer: The answer earns marks by joining evidence, method or data to a biological reason. Avoid mixing up genotype, phenotype, genes and alleles when explaining evidence.
Quick checks
Choose an answer, then check your thinking.
1. Which answer would make dna clearer?
2. What should you check before finishing an answer on this lesson?
Practice questions
Question 1
Define DNA and use it in a complete sentence about dna, genes and chromosomes.
Reveal answer and marking guidance
Answer: DNA means the genetic material that carries instructions for making proteins. In dna, genes and chromosomes, it helps explain understand DNA, genes and chromosomes.
Marking: Credit the definition and a sentence that uses the term in the lesson context.
Question 2
Explain the main sequence in DNA using the infographic.
Reveal answer and marking guidance
Answer: Understand DNA, genes and chromosomes -> Use genetic information evidence from cells and proteins -> Process data with base sequence, scale and probability language. A strong answer says why the final step follows from the first two steps.
Marking: Credit the correct order plus a biological link between the steps.
Question 3
A question gives evidence such as cell-nucleus diagrams, chromosome diagrams, base sequence information, genome contexts and protein-coding prompts. What should you do with that evidence?
Reveal answer and marking guidance
Answer: Identify the useful observation, method detail or data first. Then use base sequence, scale and probability language where relevant and explain what it shows about DNA, gene or chromosome.
Marking: Credit evidence use, relevant data handling and a clear biology explanation.
Question 4
A student writes: 'DNA is involved, so the answer is correct.' What detail is missing?
Reveal answer and marking guidance
Answer: DNA means the genetic material that carries instructions for making proteins. A better answer also uses gene (a section of DNA that codes for a protein or characteristic) and explains the evidence route: Understand DNA, genes and chromosomes then use genetic information evidence from cells and proteins. An exam-ready version could be: A gene is a section of DNA on a chromosome, and the genome is the full set of genetic information.
Marking: Credit a precise definition, a second linked term and use of evidence or model steps.
Practice ladder
Answers and marking guidance
The exact practice answers are hidden under each question so you can try first. Marks come from using the correct biology model, choosing the right calculation where needed, keeping units with values, labelling diagrams clearly, and explaining changes with precise words such as cells, enzymes, hormones, genes, adaptation, rate, evidence and uncertainty.
Common mistakes
- Using DNA, gene or chromosome as labels without explaining what they mean.
- Forgetting to connect the answer to likely evidence, such as cell-nucleus diagrams, chromosome diagrams, base sequence information, genome contexts and protein-coding prompts.
- Missing the maths or data habit: base sequence, scale and probability language.
- Falling into the common trap of mixing up genotype, phenotype, genes and alleles when explaining evidence.
Extension challenge
Create a focused revision card for dna, genes and chromosomes: three exact definitions, one model sequence, one evidence detail such as cell-nucleus diagrams, chromosome diagrams, base sequence information, genome contexts and protein-coding prompts, one data check using base sequence, scale and probability language, one common misconception, and one exam-ready explanation sentence: A gene is a section of DNA on a chromosome, and the genome is the full set of genetic information.
Reveal answer
Example answer: A complete response names the biology model, uses accurate units or observations, and explains why the evidence supports the conclusion.
Exam-board guidance
Short board notes only. Learn the core biology above first.
AQA GCSE Biology
Often links this topic to inheritance, variation and evolution through DNA and gene. Question wording and depth can vary by board.
OCR GCSE Biology
Often links this topic to inheritance, variation and evolution through DNA and gene. Question wording and depth can vary by board.
Pearson Edexcel GCSE Biology
Often links this topic to inheritance, variation and evolution through DNA and gene. Question wording and depth can vary by board.
Eduqas GCSE Biology
Often links this topic to inheritance, variation and evolution through DNA and gene. Question wording and depth can vary by board.
WJEC Wales
Often links this topic to inheritance, variation and evolution through DNA and gene. Question wording and depth can vary by board.
CCEA GCSE Biology
Often links this topic to inheritance, variation and evolution through DNA and gene. Question wording and depth can vary by board.
Next lesson
Next, continue with Meiosis, gametes and inheritance.